Extra pounds on peri- and post-menopausal women may be connected to gut bacteria living in the intestinal tract, according to a recently released study co-authored by a 性视界传媒 alumna and professor.
鈥淕ut bacteria profiles are incredibly complicated and very diverse across people,鈥 said Cara Frankenfeld, a global and community health professor at 性视界传媒.
Women whose gut microbial communities can鈥檛 turn daidzein, a compound found in soy, into something called O-desmethylangolensin are more likely to be overweight, according to .
Daidzein has been of some interest to scientists for a while because it is structurally similar to estrogen and can possibly elicit weak estrogen-like responses in peri- and post-menopausal women who tend to have lower estrogen levels, Frankenfeld said.
There are subsets of the population who don鈥檛 produce certain compounds, in this case, ODMA.
鈥淲e can tell something about people鈥檚 gut bacteria based on the presence or absence of these compounds,鈥 she said.
The idea is that certain gut bacteria profiles are associated with certain health outcomes. Peri- and post-menopausal women who have a profile that can鈥檛 produce ODMA are in a group that鈥檚 more obese, Frankenfeld said.
The cross-sectional study examined 137 peri-menopausal and 218 post-menopausal women who consumed at least three servings of soy per week. They were identified as ODMA producers or nonproducers through urine samples.
Studies have examined other age groups, but the results vary, Frankenfeld said, so it may be an age group or a hormonal status-specific condition.
It could be that producers of ODMA may be more at risk for other conditions, she said, but researchers aren鈥檛 yet able to make recommendations to women who may fall within this group.
鈥淲e wouldn鈥檛 want people to try and become producers [of ODMA],鈥 Frankenfeld said.
Scientists do know there is an obesity颅鈥揼ut bacteria relationship, she said, but more research is needed to fully understand whether and how gut bacteria influence obesity, or whether it is vice versa, or both.